A catalyst, which remains elusive, is predicted to have caused a significantly higher rate of turnover than usual in the Baserga Lab. While the lab is experiencing a depletion of Kara, Sander, and Chewie, their absence is being suppressed by an upregulation of Kat and Bennett, as well as a temporary increase of Indira. Additionally, we have observed an increase of Susan in the lab, which may or may not be associated with the decrease of Kara. Continuing work seeks to quantify the increase in the turnover number, kcat, as well as to investigate a proposed link of the kcat to Kat.
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Sander has proposed an hypothesis:
Susan is expected to be a stimulatory factor on Franziska and Erica's Kcats. However, Susan's cofactor (the puppy) has an inhibitory effect on Susan and thus nothing has changed in the lab.
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